Antibiotics safe for use in rabbits

 

 

 

 

Name of antibiotics

Remarks

Dosage
Way
Frequency

 

Amikacin

Nephrotoxic in dehydrated rabbits.

5-10 mg/kg

8-16 mg/kg

SC, IM, IV

sid, bid, tid

Amoxicillin

   (see: Remarks)

*ONLY* as injection, never orally.

Has recently been successfully used in rabbits, to treat infections due to bacteria, whose sensitivity tests indicate that amoxillin is the only effective antibiotic.

No adverse reaction has been noted with injected treatment. *Never* give orally; this has fatal consequences.

Is used sometimes to treat treponematosis.

15 mg/kg (?)

SC, IM

q second day

Azithromycin

Recommended for difficult to treat URI.

May lead to a reduction of appetite.

50mg/kg

PO

sid

Bicillin in Units

(penicillin G procaine and penicillin G benzathine)

   (see: Remarks)

*ONLY* as injection.

for treatment of bacterial infections. In rare cases, penicillin treatment leads to:

- a decreased appetite,

- the formation of sterile abscesses.

47.000–84.000 IU/kg

SC

q 2nd/3rd day

Bicillin in mg/kg

(penicillin G procaine and penicillin G benzathine)

   (see: Remarks)

*ONLY* as injection.

for treatment of bacterial infections. In rare cases, penicillin treatment leads to:

- a decreased appetite,

- the formation of sterile abscesses.

20 mg/kg – 15 mg/kg

SC

q 2nd/3rd day

 

 

 

 

 

Cephalexin

   (see: Remarks)

*ONLY* as injection.

Normally no cross reaction with Penicillin, in some cases of renal failure > nephrotoxic

10-15 mg/kg

20 mg/kg

SC

SC

bid, tid

sid

Chloramphenicol

 

Exceptionally leads to a decrease of appetite

30-50 mg/kg

15 mg/kg

PO, SC, IM

PO

sid

bid

Chlortetracycline

 

50 mg/kg

PO

bid

Ciprofloxacin

Hindered absorption, when concurrent administration of antacids.

5 – 20 mg/kg

PO

sid, bid

Clopidol

 

200 mg/kg food

 

 

Danofloxacine

 

1 - 5 mg/kg  (?)

5 mg/kg   (?)

IM

SC

 

Difloxacine

 

5 - 10 mg/kg  (?)

2,5 - 5 mg/kg

PO

SC,  IM

 

Dimetridazole

 

0.2 mg/ml water

PO

q 12 h.

Doxycycline

 

2.5 mg/kg

4 mg/kg

PO

PO

bid

sid

Enrofloxacin

   (see: Remarks)

High dosage treatment (20 mg/kg) over a longer period of time may lead to seizure.

Cartilage damage in juveniles.

In rare cases, enrofloxacin treatment leads to:

- a decreased appetite,

- the formation of sterile abscesses, if injected. This can be avoided by diluting the solution with a sterile saline solution, 50:50.

5 - 15 mg/kg

PO, SC, IM

bid-sid

Fusidic acid

In eye ointment

1 drop/eye

 

 

Gentamycin

   (see: Remarks)

Best avoided for use in rabbits

Depending on dosage: Ototoxicity

Nephrotoxic, neuromuscular block

5 – 8 mg/kg

1-2 drops/eye

SC, IM, IV

 

q 8-12 h.

tid

Marbofloxacine

Cartilage damage in juveniles

2 5 mg/kg

PO

sid

Metronidazole

3 to 5 days

20 mg/kg

PO

bid

Neomycin

Depending on dosage: ototoxicity

Nephrotoxic, neuromuscular block

30 mg/kg

PO

bid

Oxytetracycline

 

15 mg/kg

50 mg/kg

SC, IM

PO

sid, tid

bid

Penicillin G procaine

*Only* as injection.

For the treatment of Treponematosis

20.000 – 60.000 UI/kg

SC, IM

q 48 h. to q once per week

Robenidine

 

50-66 mg/kg feed

 

 

Spiramycin

   (see: Remarks)

Recommended for difficult to treat URI

Cecal enlargement has been observed, with dosage of 200 and 400 mg/kg

1 ml/kg

25 mg/kg

SC, IM

 

Streptomycin

Depending on dosage: Ototoxicity

Nephrotoxic, neuromuscular block

50 mg/kg

IM

sid

Sulfadimidene

 

1 – 5 mg/ml water

 

 

Sulfamethazine

 

100-233 mg/l water

 

 

Tetracycline

May lead to a reduction of appetite.

50 mg/kg

PO

q 8-12 h.

Trimethoprim Sulfa

 

15 - 30 mg/kg

48 mg/kg

PO

SC

bid

bid

Toltrazuril

q 24 the first 2 days, repeat after 2 days

25 mg/kg

PO

q 24 h.

Tylosin

   (see: Remarks)

A test dose of 5 mg/kg should be give to check that no adverse reaction takes place.

10 mg/kg

PO, SC, IM

bid

 

to understand the meaning of the abbreviations, click here.

 

 

 

Further information

 

Dana G. Allen, J. K Pringle, Dale A. Smith, Handbook of Veterinary Drugs. Lippincott – Raven 1998.

Elizabeth V. Hillyer and Katherine E. Quesenberry, Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery. New York: WB Saunders Co. 1997.

Frances Harcourt-Brown, Rabbit Medicine and Surgery. Butterworth-Heinemann 2001.

Kathy Laber-Laird, Paul Flecknell and M. Michael Swindle, Handbook of Rodent and Rabbit Medicine. Oxford, UK: Pergamon Press 1996.

John E. Harkness and Joseph E. Wagner, The Biology and Medicine of Rabbits and Rodents. New York: Lippincott Williams & Wilkins 1995.

Paul Flecknell, BSAVA Manual of Rabbit Medicine and Surgery. British Small Animal Veterinary Association 2000.Virginia Richardson, Rabbits: Health, Husbandry and Disease, Blackwell Science Inc. 2000.

H. Schall, Kaninchen, In: Krankheiten der Heimtiere (K Gabrisch & P Zwart, eds), Schlütersche & Co, Hannover (D); pp 1-45, 1998

 

 

 

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13    JANUARY   2004

last updated: October 2005