Moist dermatitis, green fur syndrome, caused by

Pseudomonas aeruginosa



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This skin disorder is caused by bacteria like Staphylococcus spp., Streptococcus spp., and mainly Pseudomonas aeruginosa. The later is a Gram-negative, opportunistic pathogen that lives in aerobic and poor nutritional conditions (the bacterium is able to grow in distilled water). The bacterium produced 2 pigments, pyoverdin and pyocyanin, when living in an environment with a low content of iron, which color the hair and pus oozing out of infected skin or abscesses in a characteristic blue-green.

Exudative (relating to the oozing of fluid and other materials from cells and tissues) moist dermatitis is mainly observed in rabbits exposed to constant moisture, for instance:

Leaking water bottles, or inadequate crock;


Large dewlap (fold of skin which hangs under the throat of female rabbits);

Ptyalism, due to (severe) dental problems, leading to excessive production of saliva.

M. Schoenbaum


Left: Green fur cause by the presence of Pseudomonas aeruginosa,

Right: Appearance of the fur, two days after removal of the moist source.

Clinical signs and diagnosis

The clinical signs should be sufficient for diagnosis. Even so, a bacterial culture is advisable, as a precautionary measure. The cultures of isolated bacteria will nevertheless help a proper identification of the bacterium. Sensitivity tests will furthermore help determine the most efficacious antibiotic. The bacterium is indeed difficult to treat, as it has naturally acquired resistance to many antibiotics, while living in the soil, among bacteria, yeast and fungi that secrete natural antibiotics.

Parts of the body affected by this bacterium are the dewlap, and the abdomen. Lesions are localized and diffuse and the skin is erythematous and moist. It may be accompanied by the presence of deep ulcers or abscesses. Secondary bacterial infection is possible when the condition is left untreated, with the formation of skin abscesses.




Dental disorders causing ptyalism in rabbits, from left to right: molar overgrowth, molar spur, incisors malocclusion.



The fur is carefully clipped and the inflamed skin is treated with topical antibiotics. If the infection by Pseudomonas sp. is severe, the topical treatment should be accompanied by an aggressive systemic antibiotic therapy.

The most effective antibiotics remain fluoroquinolone (e.g. enrofloxacin), gentamycin, and amikacin. Since some strains are resistant to several antibiotics, a culture accompanied by an antibiotic sensitivity test should be done.

While treating the skin problems, it is necessary to look for the primary cause of infection. This includes:

Meticulous inspection of the teeth of the rabbit, in order to detect defects of the incisors (malocclusion), the presence of spurs or of a tooth root abscess;

Verification of the drinking habits of the rabbit (crock or water bottle);

Analysis of the water that the rabbit is drinking for the presence of Pseudomonas sp.

Infections should not be neglected and left untreated. After the primary invasion of the skin, Pseudomonas bacteria tend to invade the tissues deeper and will use the circulatory blood system to disseminate throughout the body.


More detailed information on moist dermatitis in rabbits is found in:

Skin Diseases of Rabbits

by E. van Praag, A. Maurer and T. Saarony,, 2010.

Paperback, 408 pages.


Thanks are due to Dr. M. Schoenbaum (Ministry of Agriculture, Veterinary Services, Israel) for the permission to use their pictures.

Further information

Garibaldi BA, Fox JG, Musto DR. Atypical moist dermatitis in rabbits. Lab Anim Sci. 1990 Nov;40(6):652-3.

O'Donoghue PN, Whatley BF. Pseudomonas aeruginosa in rabbit fur. Lab Anim. 1971 Oct;5(2):251-5.

Schoenbaum M. Pseudomonas aeruginosa in rabbit fur. Lab Anim. 1981 Jan;15(1):5.

Wellisch G, Cohen E, Cahane Z, Kedar S, Fradis M, Podoshin L. Distribution of Pseudomonas aeruginosa serotypes in Israel. Microbiol Immunol. 1980;24(3):233-35.

Williams CS, Gibson RB. Sore dewlap: Pseudomonas aeruginosa on rabbit fur and skin. Vet Med Small Anim Clin. 1975 Aug;70(8):954-5.